One of the trends of modern mmos is that they don't really feel dangerous. In most of them, assuming you're appropriately leveled, you can pretty much go wherever you want without worry especially if you have a mount that allows you to travel past almost any enemy.
Older mmos tended to be better at making the world feel threatening. In Final Fantasy XI, for example, monsters would generally be more dangerous the further you strayed from roads, and it also had extremely punishing aggro mechanics — linking, no leashing, and different types of aggro that would punish uninformed players. Some games had higher level bosses in low level zones that would terrorize low level players if aggro'd. Sometimes monsters had skills that were devastating if you weren't prepared to deal with them.
Fractured will obviously have danger in the form of PvP, but what can we expect PvE-wise?